gcr – Übersetzung – Keybot-Wörterbuch

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La pasiréotide, un inhibiteur des récepteurs de la somatostatine plus récent, est un traitement efficace du cancer neuroendocrinien avancé (Gastrointestinal Cancer Research: GCR, PMID 23112884; Endocrine-Related Cancer, PMID 22807497
Somatostatin is a hormone made by neuroendocrine system cells in the brain and digestive system. It prevents the body from releasing growth hormone, thyroid-stimulating hormone and gastrointestinal hormones. It also reduces the activity of the digestive system. Octreotide (Sandostatin) is a somatostatin receptor blocker, which means that it blocks the action of somatostatin. Octreotide slows tumour progression in functional (hormone producing) and non-functional (not hormone producing) neuroendocrine cancers in the digestive system (Clinical Oncology: A Journal of the Royal College of Radiologists, PMID 21907552; Oncologist, PMID 22628056). Pasireotide is a newer somatostatin receptor blocker that is effective in the treatment of advanced neuroendocrine cancer (Gastrointestinal Cancer Research: GCR, PMID 23112884; Endocrine-Related Cancer, PMID 22807497).
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